Understanding the BRCA Gene

What is the BRCA Gene?

 Early detection is vital for the best treatment possible for breast cancer. While at-home breast exams and routine mammograms (based on age) are more widely known, genetic testing for those with a high-family risk can also be considered.

If you already have a high rate of breast cancer in your family, you may have heard of the BRCA gene (often called the Breast Cancer Gene) but might not know its role in your risk of developing breast cancer.

What is BRCA?

When breast cancer is inherited, it’s often associated with an abnormal gene. Known as the BReast CAncer gene and is identified as BRCA1 and BRCA2, these genes themselves do not cause breast cancer and are present in all humans. However, when working properly, the genes can help prevent breast cancer by helping repair DNA breaks (which often lead to cancer or tumor growth).

What BRCA Mutations Predict

When an abnormal change or mutation is present (inherited from the mother or the father’s side), there will be a much higher chance of developing breast cancer and ovarian cancer. The percentage that carries this mutation is small, but when present, it does impact your cancer odds and can be passed down to your offspring.

Knowing Your BRCA Mutation Risks

Having a mutation of both the BRCA1 and BRCA2 genes increases your chance of getting cancer. Still, it can also increase your chances of an early diagnosis and may have a higher-than-average chance of developing other cancers. It might mean a more aggressive form of cancer for some, too. Though the mutation can bring alarming risks, it can be tested for, and just a small percentage of those diagnosed with cancer have these mutated genes.

If identified early, some might undergo preventive procedures to reduce their risk of breast cancer. All those living with a high volume of family members that have battled or been diagnosed with cancer should talk to their doctor about the possibility of genetic testing as part of their preventive care.